STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
pdhCDihydrolipoamide acetyltransferase component ofpyruvate deshydrogenase complex. (244 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component, betasubunit.
 
 0.999
pdhD
Dihydrolipoamide dehydrogenase (E3 component ofpyruvate complex).
 0.999
pdhA
Pyruvate dehydrogenase E1 component, alphasubunit.
 
 0.996
pta
Phosphate acetyltransferase(Phosphotransacetylase).
  
 
 0.930
pta-2
Phosphate acetyltransferase(Phosphotransacetylase).
  
 
 0.922
prs
Ribose phosphate pyrophosphokinase(Phosphoribosyl pyrophosphate synthetase).
  
 0.871
MAG7330
Acyl carrier protein homolog.
  
 0.802
MAG0945
Hypothetical protein.
       0.782
MAG0080
Conserved hypothetical protein.
   
 0.735
lon
Heat shock ATP dependent protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity).
  
 
  0.698
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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