STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
pdhDDihydrolipoamide dehydrogenase (E3 component ofpyruvate complex). (541 aa)    
Predicted Functional Partners:
pdhB
Pyruvate dehydrogenase E1 component, betasubunit.
 
 0.999
pdhC
Dihydrolipoamide acetyltransferase component ofpyruvate deshydrogenase complex.
 0.999
MAG4910
Hypothetical protein.
 
 0.997
pdhA
Pyruvate dehydrogenase E1 component, alphasubunit.
  
 
 0.996
glyA
Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.933
folD
FolD bifunctional protein(Methylenetetrahydrofolate Dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
    
 0.929
prs
Ribose phosphate pyrophosphokinase(Phosphoribosyl pyrophosphate synthetase).
   
 0.926
gcdH-2
Glycine cleavage system H protein.
   
 0.913
gcdH
Glycine cleavage system H protein.
   
 0.834
MAG2110
Protein phosphatase.
  
 0.785
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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