STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhDDihydrolipoamide dehydrogenase (E3 component ofpyruvate complex). (541 aa)    
Predicted Functional Partners:
pdhA
Pyruvate dehydrogenase E1 component, alphasubunit.
 
 
 0.999
pdhB
Pyruvate dehydrogenase E1 component, betasubunit.
 
 0.999
pdhC
Dihydrolipoamide acetyltransferase component ofpyruvate deshydrogenase complex.
 0.999
MAG4910
Hypothetical protein.
 
 0.999
gcdH
Glycine cleavage system H protein.
    
 0.985
glyA
Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 0.941
prs
Ribose phosphate pyrophosphokinase(Phosphoribosyl pyrophosphate synthetase).
   
 0.930
lplA-2
Lipoate protein ligase A.
  
 
 0.928
gcdH-2
Glycine cleavage system H protein.
    
 0.928
lplA
Lipoate protein ligase A.
  
 
 0.893
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.