STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (195 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 
 0.977
hpt
Hypoxanthine guanine phosphoribosyltransferase(HGPRT); Belongs to the purine/pyrimidine phosphoribosyltransferase family.
    
 0.939
adk
Adenylate kinase (ATP AMP transphosphorylase); Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
   
 
 0.927
pyk
Pyruvate kinase (PK); Belongs to the pyruvate kinase family.
  
 
 0.924
MAG5910
5'Nucleotidase; Belongs to the 5'-nucleotidase family.
    
 0.923
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.907
MAG2110
Protein phosphatase.
   
   0.843
pknB
Serine/threonine protein kinase.
      0.811
rpe
Ribulose phosphate 3 epimerase(Pentose 5 phosphate 3 epimerase).
  
 
 0.809
pgiB
Glucose 6 phosphate isomerase; Belongs to the GPI family.
  
  
 0.784
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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