pknB protein (Mycoplasma agalactiae PG2) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

pknB

Serine/threonine protein kinase. (331 aa)

Predicted Functional Partners:

MAG2110

0.997

engC

0.919

rpe

0.846

gmk

0.809

deoC

0.778

MAG2440

0.746

ptsG

0.741

rpmH

0.731

ftsZ

0.694

hprK

0.692

Your Current Organism:

Mycoplasma agalactiae PG2

NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAG2110	engC	MAG2110	MAG2130	Protein phosphatase.	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.815
MAG2110	gmk	MAG2110	MAG2100	Protein phosphatase.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.837
MAG2110	pknB	MAG2110	MAG2120	Protein phosphatase.	Serine/threonine protein kinase.	0.997
MAG2110	rpe	MAG2110	MAG2140	Protein phosphatase.	Ribulose phosphate 3 epimerase(Pentose 5 phosphate 3 epimerase).	0.752
MAG2440	hprK	MAG2440	MAG0890	Hypothetical protein.	HPr kinase/phosphorylase; Belongs to the HPrK/P family.	0.659
MAG2440	pknB	MAG2440	MAG2120	Hypothetical protein.	Serine/threonine protein kinase.	0.746
MAG2440	ptsG	MAG2440	MAG3250	Hypothetical protein.	PtsG.	0.963
MAG2440	rpe	MAG2440	MAG2140	Hypothetical protein.	Ribulose phosphate 3 epimerase(Pentose 5 phosphate 3 epimerase).	0.722
deoC	pknB	MAG5130	MAG2120	Deoxyribose phosphate aldolase(Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.	Serine/threonine protein kinase.	0.778
deoC	rpmH	MAG5130	MAG7500	Deoxyribose phosphate aldolase(Phosphodeoxyriboaldolase) (Deoxyriboaldolase); Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.	50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.	0.607
engC	MAG2110	MAG2130	MAG2110	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Protein phosphatase.	0.815
engC	gmk	MAG2130	MAG2100	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	0.770
engC	pknB	MAG2130	MAG2120	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Serine/threonine protein kinase.	0.919
engC	rpe	MAG2130	MAG2140	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	Ribulose phosphate 3 epimerase(Pentose 5 phosphate 3 epimerase).	0.979
ftsZ	pknB	MAG3710	MAG2120	Cell division protein ftsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.	Serine/threonine protein kinase.	0.694
gmk	MAG2110	MAG2100	MAG2110	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Protein phosphatase.	0.837
gmk	engC	MAG2100	MAG2130	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	GTPase EngC; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.	0.770
gmk	pknB	MAG2100	MAG2120	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Serine/threonine protein kinase.	0.809
gmk	rpe	MAG2100	MAG2140	Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.	Ribulose phosphate 3 epimerase(Pentose 5 phosphate 3 epimerase).	0.801
hprK	MAG2440	MAG0890	MAG2440	HPr kinase/phosphorylase; Belongs to the HPrK/P family.	Hypothetical protein.	0.659