Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
gcdH-2Glycine cleavage system H protein. (125 aa)    
Predicted Functional Partners:
pdhD
Dihydrolipoamide dehydrogenase (E3 component ofpyruvate complex).
   
 0.913
MAG7330
Acyl carrier protein homolog.
  
 
 0.761
glyA
Serine hydroxymethyltransferase (Serinemethylase) (SHMT); Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.693
folD
FolD bifunctional protein(Methylenetetrahydrofolate Dehydrogenase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
  
 
 0.677
MAG0060
Lipoate protein ligase A, truncated in C terminal.
   
 0.630
lplA
Lipoate protein ligase A.
   
 0.630
lplA-2
Lipoate protein ligase A.
   
 0.630
pdhC
Dihydrolipoamide acetyltransferase component ofpyruvate deshydrogenase complex.
  
 0.597
MAG4910
Hypothetical protein.
  
 0.597
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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