STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hisSHistidyl tRNA synthetase (Histidine tRNAligase) (HisRS). (443 aa)    
Predicted Functional Partners:
aspS
Aspartyl tRNA synthetase (Aspartate tRNAligase) (AspRS); Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.
  
  
 0.923
thrS
Threonyl tRNA synthetase; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.886
secD
Protein export membrane protein.
  
  
 0.835
fmt
Methionyl tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
  
 0.825
pcrA
ATP dependent helicase.
  
  
 0.752
MAG4050
Conserved hypothetical protein.
    
  0.748
MAG4060
Conserved hypothetical protein, truncated in C terminal.
    
  0.748
metS
Methionyl tRNA synthetase (Methionine tRNAligase).
  
 
 0.730
leuS
Leucyl tRNA synthetase (Leucine tRNA ligase); Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.703
valS
Valyl tRNA synthetase (Valine tRNA ligase)(VALRS); Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.
  
 
 0.678
Your Current Organism:
Mycoplasma agalactiae PG2
NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2
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