xer1 protein (Mycoplasma agalactiae PG2) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

xer1

Integrase recombinase. (249 aa)

Predicted Functional Partners:

vpmaZ

0.787

vpmaW

0.629

vpmaX

0.618

vpmaY

0.618

vpmaU

0.618

topA

0.554

vpmaV

0.513

rpsI

0.469

MAG7120

0.465

rpsJ

0.460

Your Current Organism:

Mycoplasma agalactiae PG2

NCBI taxonomy Id: 347257
Other names: M. agalactiae PG2, Mycoplasma agalactiae str. PG2, Mycoplasma agalactiae strain PG2

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MAG7120	xer1	MAG7120	MAG7110	Conserved hypothetical protein.	Integrase recombinase.	0.465
rpsI	rpsJ	MAG4560	MAG5470	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	0.997
rpsI	topA	MAG4560	MAG2750	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.607
rpsI	xer1	MAG4560	MAG7110	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	Integrase recombinase.	0.469
rpsJ	rpsI	MAG5470	MAG4560	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.997
rpsJ	xer1	MAG5470	MAG7110	30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.	Integrase recombinase.	0.460
topA	rpsI	MAG2750	MAG4560	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.	0.607
topA	vpmaZ	MAG2750	MAG7100	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Variable surface lipoprotein D (VpmaZprecursor).	0.411
topA	xer1	MAG2750	MAG7110	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	Integrase recombinase.	0.554
vpmaU	vpmaY	MAG7090	MAG7080	Variable surface lipoprotein U (VpmaUprecursor).	Variable surface lipoprotein Y (VpmaYprecursor).	0.507
vpmaU	xer1	MAG7090	MAG7110	Variable surface lipoprotein U (VpmaUprecursor).	Integrase recombinase.	0.618
vpmaV	vpmaW	MAG7050	MAG7060	Variable surface lipoprotein V (VpmaVprecursor).	Variable surface lipoprotein W (VpmaWprecursor).	0.572
vpmaV	xer1	MAG7050	MAG7110	Variable surface lipoprotein V (VpmaVprecursor).	Integrase recombinase.	0.513
vpmaW	vpmaV	MAG7060	MAG7050	Variable surface lipoprotein W (VpmaWprecursor).	Variable surface lipoprotein V (VpmaVprecursor).	0.572
vpmaW	xer1	MAG7060	MAG7110	Variable surface lipoprotein W (VpmaWprecursor).	Integrase recombinase.	0.629
vpmaX	xer1	MAG7070	MAG7110	Variable surface lipoprotein A (vpmaXprecusor).	Integrase recombinase.	0.618
vpmaY	vpmaU	MAG7080	MAG7090	Variable surface lipoprotein Y (VpmaYprecursor).	Variable surface lipoprotein U (VpmaUprecursor).	0.507
vpmaY	xer1	MAG7080	MAG7110	Variable surface lipoprotein Y (VpmaYprecursor).	Integrase recombinase.	0.618
vpmaZ	topA	MAG7100	MAG2750	Variable surface lipoprotein D (VpmaZprecursor).	DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]	0.411
vpmaZ	xer1	MAG7100	MAG7110	Variable surface lipoprotein D (VpmaZprecursor).	Integrase recombinase.	0.787