STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2P5CNM3ADF/Cofilin/Destrin; Belongs to the actin-binding proteins ADF family. (146 aa)    
Predicted Functional Partners:
A0A2P5CA65
Adenylyl cyclase-associated protein; Belongs to the CAP family.
   
 0.711
A0A2P5D3J9
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
  
 0.695
A0A2P5CM88
Guanine nucleotide-binding protein, beta subunit.
   
 
 0.692
A0A2P5DAC5
Adenylate cyclase-associated CAP.
   
 0.658
A0A2P5C083
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
  
 0.656
A0A2P5CN47
Profilin; Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations.
   
 0.580
A0A2P5AVT0
Actin family.
   
 0.573
A0A2P5B835
Actin family.
   
 0.573
A0A2P5BJJ2
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
   
 
 0.566
A0A2P5ABC5
Actin family.
   
 0.563
Your Current Organism:
Parasponia andersonii
NCBI taxonomy Id: 3476
Other names: P. andersonii, Parasponia andersonii Planch.
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.