Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
KRN95344.1Transcriptional regulator. (246 aa)    
Predicted Functional Partners:
pts18CBA
N-acetylglucosamine and glucose PTS, EIICBA.
  
 
 0.983
KRN95343.1
Lysozyme.
 
     0.702
KRN97093.1
Xylose operon regulator.
 
 
 0.631
rbsK
Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.
    
 0.615
pmi
Mannose-6-phosphate isomerase; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
 
  0.608
nagB
Glucosamine-6-phosphate isomerase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
    
 0.596
zwf
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
    
 0.578
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
    
 0.571
KRN95750.1
PTS system, mannose-specific IIAB component.
    
 0.543
KRN95345.1
Gluconokinase; Belongs to the FGGY kinase family.
 
     0.541
Your Current Organism:
Lactobacillus siliginis
NCBI taxonomy Id: 348151
Other names: DSM 22696, JCM 16155, KCTC 3985, L. siliginis, Lactobacillus siliginis Aslam et al. 2006, NBRC 101315, strain M1-212
Server load: low (22%) [HD]