| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRN93310.1 | KRN93311.1 | IV55_GL001053 | IV55_GL001054 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Xanthine uracil permease. | 0.990 |
| KRN93310.1 | KRN94536.1 | IV55_GL001053 | IV55_GL000522 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | 0.937 |
| KRN93310.1 | KRN95432.1 | IV55_GL001053 | IV55_GL001892 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | RdgB HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.935 |
| KRN93310.1 | apt | IV55_GL001053 | IV55_GL002043 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.944 |
| KRN93310.1 | deoD | IV55_GL001053 | IV55_GL001550 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Purine nucleoside phosphorylase. | 0.963 |
| KRN93310.1 | folQ | IV55_GL001053 | IV55_GL000459 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Hypothetical protein. | 0.935 |
| KRN93310.1 | gmk | IV55_GL001053 | IV55_GL000756 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.955 |
| KRN93310.1 | gmk2 | IV55_GL001053 | IV55_GL001325 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Guanylate kinase. | 0.955 |
| KRN93310.1 | guaA | IV55_GL001053 | IV55_GL000523 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.986 |
| KRN93310.1 | hprT | IV55_GL001053 | IV55_GL000965 | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.946 |
| KRN93311.1 | KRN93310.1 | IV55_GL001054 | IV55_GL001053 | Xanthine uracil permease. | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.990 |
| KRN93311.1 | guaA | IV55_GL001054 | IV55_GL000523 | Xanthine uracil permease. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.600 |
| KRN94536.1 | KRN93310.1 | IV55_GL000522 | IV55_GL001053 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenine guanine phosphoribosyltransferase-like protein; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.937 |
| KRN94536.1 | KRN95432.1 | IV55_GL000522 | IV55_GL001892 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | RdgB HAM1 family non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.939 |
| KRN94536.1 | apt | IV55_GL000522 | IV55_GL002043 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.499 |
| KRN94536.1 | folQ | IV55_GL000522 | IV55_GL000459 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypothetical protein. | 0.939 |
| KRN94536.1 | gmk | IV55_GL000522 | IV55_GL000756 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.622 |
| KRN94536.1 | gmk2 | IV55_GL000522 | IV55_GL001325 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Guanylate kinase. | 0.519 |
| KRN94536.1 | guaA | IV55_GL000522 | IV55_GL000523 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.999 |
| KRN94536.1 | hprT | IV55_GL000522 | IV55_GL000965 | IMP dehydrogenase GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. | Hypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.946 |
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