STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nrdFRibonucleotide-diphosphate reductase subunit beta. (325 aa)    
Predicted Functional Partners:
nrdI
NrdI family protein; Belongs to the NrdI family.
 
 0.999
nrdE
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 0.999
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.969
ndk
Nucleoside diphosphate kinase; Belongs to the NDK family.
     
 0.967
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.960
gmk2
Guanylate kinase.
     
 0.960
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
     
 0.954
KRN96560.1
Hypothetical protein.
 
  
 0.949
cmk
Cytidylate kinase.
    
 0.944
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.944
Your Current Organism:
Lactobacillus siliginis
NCBI taxonomy Id: 348151
Other names: DSM 22696, JCM 16155, KCTC 3985, L. siliginis, Lactobacillus siliginis Aslam et al. 2006, NBRC 101315, strain M1-212
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.