Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
hsp20AHsp20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family. (124 aa)    
Predicted Functional Partners:
gap
Glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating).
 
 
 0.903
hsp20B
Hsp20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
     
 
0.900
hsp20C
Hsp20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
hsp20D
Hsp20-type molecular chaperone; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
dnaK
Hsp70-type molecular chaperone DnaK; Acts as a chaperone.
  
 
 0.677
cdc48b
AAA-type ATPase (CDC48 subfamily).
 
 
 0.599
grpE
DnaJ/DnaK ATPase stimulator GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several round [...]
  
 
 0.597
cdc48a
AAA-type ATPase (CDC48 subfamily).
 
 
 0.593
cdc48c
AAA-type ATPase (CDC48 subfamily).
 
 
 0.588
tif1A1
Translation initiation factor aIF-1A; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits.
     
 0.534
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
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