node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NP_0446A | endA | NP_0446A | NP_0444A | Homolog to DNA topoisomerase 1. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.743 |
NP_0446A | trpS | NP_0446A | NP_0442A | Homolog to DNA topoisomerase 1. | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). | 0.684 |
NP_2146A | cca | NP_2146A | NP_0320A | cro/C1 family transcription regulator. | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | 0.527 |
NP_2146A | dnaG | NP_2146A | NP_4538A | cro/C1 family transcription regulator. | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.653 |
NP_2146A | endA | NP_2146A | NP_0444A | cro/C1 family transcription regulator. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.605 |
NP_2146A | rpe | NP_2146A | NP_3964A | cro/C1 family transcription regulator. | Rpa-associated phosphoesterase. | 0.433 |
NP_2146A | spt5 | NP_2146A | NP_0814A | cro/C1 family transcription regulator. | Transcription elongation factor Spt5; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.536 |
NP_5082A | endA | NP_5082A | NP_0444A | DUF188 family protein. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.603 |
NP_5082A | priL | NP_5082A | NP_0686A | DUF188 family protein. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.479 |
NP_5082A | spt5 | NP_5082A | NP_0814A | DUF188 family protein. | Transcription elongation factor Spt5; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.449 |
cca | NP_2146A | NP_0320A | NP_2146A | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | cro/C1 family transcription regulator. | 0.527 |
cca | dnaG | NP_0320A | NP_4538A | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 0.695 |
cca | endA | NP_0320A | NP_0444A | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.750 |
cca | orc1 | NP_0320A | NP_0596A | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Orc1-type DNA replication protein; Involved in regulation of DNA replication. | 0.458 |
cca | spt5 | NP_0320A | NP_0814A | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | Transcription elongation factor Spt5; Stimulates transcription elongation; Belongs to the archaeal Spt5 family. | 0.689 |
dnaG | NP_2146A | NP_4538A | NP_2146A | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | cro/C1 family transcription regulator. | 0.653 |
dnaG | cca | NP_4538A | NP_0320A | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | tRNA adenylyltransferase, CCA-adding; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. | 0.695 |
dnaG | endA | NP_4538A | NP_0444A | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | tRNA-splicing endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity). | 0.787 |
dnaG | orc1 | NP_4538A | NP_0596A | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Orc1-type DNA replication protein; Involved in regulation of DNA replication. | 0.735 |
dnaG | priL | NP_4538A | NP_0686A | DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.780 |