Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
sec11Signal peptidase I. (276 aa)    
Predicted Functional Partners:
polD1
DNA-directed DNA polymerase D exonuclease subunit DP1; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family.
 
     0.926
aglB
Dolichyl-monophosphooligosaccharide--protein glycotransferase AglB.
  
  
 0.861
artA
Archaeosortase A; Transpeptidase that recognizes and modifies its substrate by proteolytic cleavage of a sorting signal. Following cleavage, a covalent intermediate is formed via a thioester bond between the archaeosortase and its substrate, which is then transferred and covalently attached to the cell membrane.
  
   
 0.854
atpE
A-type ATP synthase subunit E; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.825
atpF
A-type ATP synthase subunit F; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
 
  0.801
pibD
Prepilin/preflagellin peptidase.
 
   
 0.794
atpK
A-type ATP synthase subunit K.
 
  
 0.792
atpC
A-type ATP synthase subunit C; Produces ATP from ADP in the presence of a proton gradient across the membrane.
 
  
 0.759
sepF
Probable SepF protein.
  
     0.751
rnhB
Ribonuclease H, type 2; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family.
  
  
 0.748
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
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