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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
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[Homology]
Score
pdaDPyruvoyl-dependent arginine decarboxylase. (159 aa)    
Predicted Functional Partners:
speB2
Agmatinase; Belongs to the arginase family.
    
 0.929
NP_4482A
Uncharacterized protein.
       0.919
nos
Nitric-oxide synthase; Catalyzes the production of nitric oxide. Belongs to the NOS family. Bacterial NOS oxygenase subfamily.
     
  0.900
pan1
Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...]
       0.886
argH
Argininosuccinate lyase.
     
  0.800
ala
Alanine dehydrogenase; Catalyzes the NAD(+)-dependent oxidative deamination of L- alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate; Belongs to the ornithine cyclodeaminase/mu-crystallin family. Archaeal alanine dehydrogenase subfamily.
      
 0.764
NP_1474A
GNAT family acetyltransferase.
  
     0.620
NP_0898A
Helicase domain protein; See the associated misc_feature for pseudogene details; product: GNAT family acetyltransferase (nonfunctional); EC_number: 2.3.1.-.
  
     0.594
sdhD
Succinate dehydrogenase subunit D; Deleted EC_number 1.3.99.1.
  
     0.594
uvrD
Repair helicase UvrD.
  
     0.593
Your Current Organism:
Natronomonas pharaonis
NCBI taxonomy Id: 348780
Other names: N. pharaonis DSM 2160, Natronomonas pharaonis ATCC 35678, Natronomonas pharaonis DSM 2160, Natronomonas pharaonis Gabara, Natronomonas pharaonis JCM 8858, Natronomonas pharaonis str. DSM 2160, Natronomonas pharaonis strain DSM 2160
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