STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV05_08397POLXc domain-containing protein. (716 aa)    
Predicted Functional Partners:
PV05_08124
Polynucleotide kinase 3'-phosphatase.
    
 0.889
PV05_00251
DNA ligase.
  
 0.877
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.860
PV05_10348
SAP domain-containing protein.
    
 0.854
PV05_07438
DNA ligase.
  
 0.845
PV05_04065
DNA ligase.
  
 0.845
PV05_03342
Exodeoxyribonuclease III.
    
 0.834
PV05_02563
DNA_LIGASE_A3 domain-containing protein.
  
 0.820
PV05_01170
DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family.
    
 0.814
PV05_00264
DNA polymerase.
   
 0.808
Your Current Organism:
Exophiala xenobiotica
NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica
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