STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PV05_05756Aldolase_II domain-containing protein. (309 aa)    
Predicted Functional Partners:
ADI1
1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase; Catalyzes the formation of formate and 2-keto-4- methylthiobutyrate (KMTB) from 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
  
 
 0.716
PV05_04860
Uncharacterized protein.
  
 
 0.715
MRI1
Methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). Belongs to the eIF-2B alpha/beta/delta subunits family. MtnA subfamily.
  
 
 0.707
PV05_00372
Uncharacterized protein.
  
 
 0.694
PV05_05713
Uncharacterized protein.
  
 
 0.694
PV05_03941
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.613
PV05_11307
FBPase domain-containing protein; Belongs to the FBPase class 1 family.
   
 
 0.604
PV05_04242
2,3-diketo-5-methylthio-1-phosphopentane phosphatase.
  
 
 0.594
PV05_10194
AP_endonuc_2 domain-containing protein.
  
 
 0.569
PV05_00720
Glyceraldehyde-3-phosphate dehydrogenase.
     
 0.567
Your Current Organism:
Exophiala xenobiotica
NCBI taxonomy Id: 348802
Other names: CBS 118157, E. xenobiotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.