node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SES80165.1 | SET32201.1 | SAMN05660429_00424 | SAMN05660429_01533 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Asparagine synthase (glutamine-hydrolysing). | 0.405 |
SES80165.1 | SET32228.1 | SAMN05660429_00424 | SAMN05660429_01534 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 23S rRNA (guanine745-N1)-methyltransferase. | 0.488 |
SES80165.1 | gcvP | SAMN05660429_00424 | SAMN05660429_02779 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.490 |
SET32201.1 | SES80165.1 | SAMN05660429_01533 | SAMN05660429_00424 | Asparagine synthase (glutamine-hydrolysing). | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.405 |
SET32201.1 | SET32228.1 | SAMN05660429_01533 | SAMN05660429_01534 | Asparagine synthase (glutamine-hydrolysing). | 23S rRNA (guanine745-N1)-methyltransferase. | 0.608 |
SET32228.1 | SES80165.1 | SAMN05660429_01534 | SAMN05660429_00424 | 23S rRNA (guanine745-N1)-methyltransferase. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.488 |
SET32228.1 | SET32201.1 | SAMN05660429_01534 | SAMN05660429_01533 | 23S rRNA (guanine745-N1)-methyltransferase. | Asparagine synthase (glutamine-hydrolysing). | 0.608 |
SET32228.1 | SET37566.1 | SAMN05660429_01534 | SAMN05660429_01649 | 23S rRNA (guanine745-N1)-methyltransferase. | Hypothetical protein; Belongs to the cytochrome P450 family. | 0.679 |
SET32228.1 | dapE | SAMN05660429_01534 | SAMN05660429_01540 | 23S rRNA (guanine745-N1)-methyltransferase. | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 0.455 |
SET32228.1 | gcvP | SAMN05660429_01534 | SAMN05660429_02779 | 23S rRNA (guanine745-N1)-methyltransferase. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.721 |
SET37566.1 | SET32228.1 | SAMN05660429_01649 | SAMN05660429_01534 | Hypothetical protein; Belongs to the cytochrome P450 family. | 23S rRNA (guanine745-N1)-methyltransferase. | 0.679 |
dapE | SET32228.1 | SAMN05660429_01540 | SAMN05660429_01534 | Succinyldiaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. | 23S rRNA (guanine745-N1)-methyltransferase. | 0.455 |
gcvP | SES80165.1 | SAMN05660429_02779 | SAMN05660429_00424 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.490 |
gcvP | SET32228.1 | SAMN05660429_02779 | SAMN05660429_01534 | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 23S rRNA (guanine745-N1)-methyltransferase. | 0.721 |