node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SET17128.1 | SET32263.1 | SAMN05660429_01146 | SAMN05660429_01535 | Hypothetical protein. | Hypothetical protein. | 0.771 |
SET17128.1 | queE | SAMN05660429_01146 | SAMN05660429_01840 | Hypothetical protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.525 |
SET32263.1 | SET17128.1 | SAMN05660429_01535 | SAMN05660429_01146 | Hypothetical protein. | Hypothetical protein. | 0.771 |
SET32263.1 | queE | SAMN05660429_01535 | SAMN05660429_01840 | Hypothetical protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.429 |
SET45984.1 | SET46071.1 | SAMN05660429_01838 | SAMN05660429_01841 | Methyltransferase domain-containing protein. | Hypothetical protein. | 0.550 |
SET45984.1 | queC | SAMN05660429_01838 | SAMN05660429_01839 | Methyltransferase domain-containing protein. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.774 |
SET45984.1 | queE | SAMN05660429_01838 | SAMN05660429_01840 | Methyltransferase domain-containing protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.550 |
SET46071.1 | SET45984.1 | SAMN05660429_01841 | SAMN05660429_01838 | Hypothetical protein. | Methyltransferase domain-containing protein. | 0.550 |
SET46071.1 | queC | SAMN05660429_01841 | SAMN05660429_01839 | Hypothetical protein. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.550 |
SET46071.1 | queE | SAMN05660429_01841 | SAMN05660429_01840 | Hypothetical protein. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.773 |
SET51854.1 | guaA | SAMN05660429_02028 | SAMN05660429_00196 | 6-pyruvoyl tetrahydropterin synthase. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.404 |
SET51854.1 | queC | SAMN05660429_02028 | SAMN05660429_01839 | 6-pyruvoyl tetrahydropterin synthase. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.888 |
SET51854.1 | queE | SAMN05660429_02028 | SAMN05660429_01840 | 6-pyruvoyl tetrahydropterin synthase. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.945 |
SET51854.1 | queF | SAMN05660429_02028 | SAMN05660429_02108 | 6-pyruvoyl tetrahydropterin synthase. | 7-cyano-7-deazaguanine reductase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.795 |
glmS | guaA | SAMN05660429_02337 | SAMN05660429_00196 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.532 |
glmS | purF | SAMN05660429_02337 | SAMN05660429_00526 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.679 |
glmS | queC | SAMN05660429_02337 | SAMN05660429_01839 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | preQ(0) biosynthesis protein QueC; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. | 0.595 |
glmS | queE | SAMN05660429_02337 | SAMN05660429_01840 | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. | 0.632 |
guaA | SET51854.1 | SAMN05660429_00196 | SAMN05660429_02028 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 6-pyruvoyl tetrahydropterin synthase. | 0.404 |
guaA | glmS | SAMN05660429_00196 | SAMN05660429_02337 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Glutamine--fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.532 |