STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SET66790.1Vitamin B12 transport system substrate-binding protein. (282 aa)    
Predicted Functional Partners:
SET66919.1
Iron complex transport system permease protein; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 0.999
SET66948.1
Iron complex transport system ATP-binding protein.
 
 0.998
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.859
SET66855.1
cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
 
     0.858
SET66754.1
Vitamin B12 transporter.
 
  
 0.670
hisI
phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family.
   
   0.554
SET00325.1
iron(III) transport system substrate-binding protein.
  
  
 0.538
SES80165.1
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
   
 0.508
SET84976.1
Precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase.
     
 0.431
SET00282.1
iron(III) transport system permease protein.
   
    0.407
Your Current Organism:
Thalassotalea agarivorans
NCBI taxonomy Id: 349064
Other names: BCRC 17492, DSM 19706, JCM 13379, T. agarivorans, Thalassomonas agarivorans, Thalassomonas agarivorans Jean et al. 2006, Thalassotalea agarivorans (Jean et al. 2006) Zhang et al. 2014, marine bacterium JAMB-A33, strain TMA1
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