node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM21708.1 | SDM30104.1 | SAMN05660299_00438 | SAMN05660299_00623 | DNA topoisomerase-3. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.609 |
SDM21708.1 | era | SAMN05660299_00438 | SAMN05660299_00625 | DNA topoisomerase-3. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.465 |
SDM21708.1 | polA | SAMN05660299_00438 | SAMN05660299_00110 | DNA topoisomerase-3. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.825 |
SDM21708.1 | recR | SAMN05660299_00438 | SAMN05660299_01846 | DNA topoisomerase-3. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.437 |
SDM21708.1 | topA | SAMN05660299_00438 | SAMN05660299_01043 | DNA topoisomerase-3. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.559 |
SDM21708.1 | ybeY | SAMN05660299_00438 | SAMN05660299_00627 | DNA topoisomerase-3. | Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.459 |
SDM30104.1 | SDM21708.1 | SAMN05660299_00623 | SAMN05660299_00438 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA topoisomerase-3. | 0.609 |
SDM30104.1 | SDM30142.1 | SAMN05660299_00623 | SAMN05660299_00624 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Hemolysin, contains CBS domains. | 0.675 |
SDM30104.1 | SDM30214.1 | SAMN05660299_00623 | SAMN05660299_00626 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.619 |
SDM30104.1 | SDM30288.1 | SAMN05660299_00623 | SAMN05660299_00628 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Phosphate starvation-inducible protein PhoH. | 0.869 |
SDM30104.1 | cinA | SAMN05660299_00623 | SAMN05660299_00930 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Nicotinamide-nucleotide amidase; Belongs to the CinA family. | 0.485 |
SDM30104.1 | era | SAMN05660299_00623 | SAMN05660299_00625 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.855 |
SDM30104.1 | polA | SAMN05660299_00623 | SAMN05660299_00110 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.497 |
SDM30104.1 | recR | SAMN05660299_00623 | SAMN05660299_01846 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA replication and repair protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. | 0.946 |
SDM30104.1 | topA | SAMN05660299_00623 | SAMN05660299_01043 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | DNA topoisomerase-1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.609 |
SDM30104.1 | ybeY | SAMN05660299_00623 | SAMN05660299_00627 | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | Probable rRNA maturation factor; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.648 |
SDM30142.1 | SDM30104.1 | SAMN05660299_00624 | SAMN05660299_00623 | Hemolysin, contains CBS domains. | DNA replication and repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.675 |
SDM30142.1 | SDM30214.1 | SAMN05660299_00624 | SAMN05660299_00626 | Hemolysin, contains CBS domains. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.639 |
SDM30142.1 | SDM30288.1 | SAMN05660299_00624 | SAMN05660299_00628 | Hemolysin, contains CBS domains. | Phosphate starvation-inducible protein PhoH. | 0.685 |
SDM30142.1 | era | SAMN05660299_00624 | SAMN05660299_00625 | Hemolysin, contains CBS domains. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.744 |