node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM05515.1 | SDM71479.1 | SAMN05660299_00096 | SAMN05660299_01410 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.527 |
SDM05515.1 | coaD | SAMN05660299_00096 | SAMN05660299_00949 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.734 |
SDM05515.1 | coaE | SAMN05660299_00096 | SAMN05660299_00108 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.595 |
SDM05515.1 | guaA | SAMN05660299_00096 | SAMN05660299_01283 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | GMP synthase (glutamine-hydrolysing); Catalyzes the synthesis of GMP from XMP. | 0.437 |
SDM05515.1 | ispH | SAMN05660299_00096 | SAMN05660299_00945 | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.565 |
SDM47247.1 | SDM47312.1 | SAMN05660299_00948 | SAMN05660299_00950 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | Hypothetical protein. | 0.822 |
SDM47247.1 | coaD | SAMN05660299_00948 | SAMN05660299_00949 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.961 |
SDM47247.1 | der | SAMN05660299_00948 | SAMN05660299_00946 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.740 |
SDM47247.1 | ispH | SAMN05660299_00948 | SAMN05660299_00945 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.526 |
SDM47247.1 | plsY | SAMN05660299_00948 | SAMN05660299_00947 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.630 |
SDM47312.1 | SDM47247.1 | SAMN05660299_00950 | SAMN05660299_00948 | Hypothetical protein. | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD. | 0.822 |
SDM47312.1 | coaD | SAMN05660299_00950 | SAMN05660299_00949 | Hypothetical protein. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.783 |
SDM47312.1 | der | SAMN05660299_00950 | SAMN05660299_00946 | Hypothetical protein. | GTP-binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.596 |
SDM47312.1 | ispH | SAMN05660299_00950 | SAMN05660299_00945 | Hypothetical protein. | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. | 0.685 |
SDM47312.1 | plsY | SAMN05660299_00950 | SAMN05660299_00947 | Hypothetical protein. | Glycerol-3-phosphate acyltransferase PlsY; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. | 0.596 |
SDM71479.1 | SDM05515.1 | SAMN05660299_01410 | SAMN05660299_00096 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.527 |
SDM71479.1 | coaD | SAMN05660299_01410 | SAMN05660299_00949 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.796 |
SDM71479.1 | coaE | SAMN05660299_01410 | SAMN05660299_00108 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.706 |
SDM71479.1 | coaX | SAMN05660299_01410 | SAMN05660299_01474 | Phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.848 |
coaD | SDM05515.1 | SAMN05660299_00949 | SAMN05660299_00096 | Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Riboflavin kinase / FMN adenylyltransferase; Belongs to the ribF family. | 0.734 |