node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM03193.1 | SDM51714.1 | SAMN05660299_00027 | SAMN05660299_01027 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | Exodeoxyribonuclease-3. | 0.938 |
SDM03193.1 | nth | SAMN05660299_00027 | SAMN05660299_02596 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.637 |
SDM03193.1 | polA | SAMN05660299_00027 | SAMN05660299_00110 | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.415 |
SDM51714.1 | SDM03193.1 | SAMN05660299_01027 | SAMN05660299_00027 | Exodeoxyribonuclease-3. | A/G-specific DNA-adenine glycosylase; Adenine glycosylase active on G-A mispairs. | 0.938 |
SDM51714.1 | nfo | SAMN05660299_01027 | SAMN05660299_01224 | Exodeoxyribonuclease-3. | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | 0.941 |
SDM51714.1 | nth | SAMN05660299_01027 | SAMN05660299_02596 | Exodeoxyribonuclease-3. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.991 |
SDM51714.1 | polA | SAMN05660299_01027 | SAMN05660299_00110 | Exodeoxyribonuclease-3. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.956 |
SDN36848.1 | SDN36884.1 | SAMN05660299_02593 | SAMN05660299_02594 | ADP-ribosylglycohydrolase. | Ribulose-bisphosphate carboxylase large chain. | 0.705 |
SDN36848.1 | SDN36917.1 | SAMN05660299_02593 | SAMN05660299_02595 | ADP-ribosylglycohydrolase. | Uncharacterized protein. | 0.715 |
SDN36848.1 | nth | SAMN05660299_02593 | SAMN05660299_02596 | ADP-ribosylglycohydrolase. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.715 |
SDN36884.1 | SDN36848.1 | SAMN05660299_02594 | SAMN05660299_02593 | Ribulose-bisphosphate carboxylase large chain. | ADP-ribosylglycohydrolase. | 0.705 |
SDN36884.1 | SDN36917.1 | SAMN05660299_02594 | SAMN05660299_02595 | Ribulose-bisphosphate carboxylase large chain. | Uncharacterized protein. | 0.868 |
SDN36884.1 | nth | SAMN05660299_02594 | SAMN05660299_02596 | Ribulose-bisphosphate carboxylase large chain. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.773 |
SDN36917.1 | SDN36848.1 | SAMN05660299_02595 | SAMN05660299_02593 | Uncharacterized protein. | ADP-ribosylglycohydrolase. | 0.715 |
SDN36917.1 | SDN36884.1 | SAMN05660299_02595 | SAMN05660299_02594 | Uncharacterized protein. | Ribulose-bisphosphate carboxylase large chain. | 0.868 |
SDN36917.1 | nth | SAMN05660299_02595 | SAMN05660299_02596 | Uncharacterized protein. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.866 |
mutM | nth | SAMN05660299_00109 | SAMN05660299_02596 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.699 |
mutM | polA | SAMN05660299_00109 | SAMN05660299_00110 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.990 |
nfo | SDM51714.1 | SAMN05660299_01224 | SAMN05660299_01027 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | Exodeoxyribonuclease-3. | 0.941 |
nfo | nth | SAMN05660299_01224 | SAMN05660299_02596 | Endonuclease IV; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. | DNA-(apurinic or apyrimidinic site) lyase; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.725 |