node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP69232.1 | ABP70010.1 | Rsph17025_0326 | Rsph17025_1109 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | 0.927 |
ABP69232.1 | ABP71374.1 | Rsph17025_0326 | Rsph17025_2486 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.905 |
ABP69232.1 | ABP71464.1 | Rsph17025_0326 | Rsph17025_2576 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.906 |
ABP69232.1 | folE2 | Rsph17025_0326 | Rsph17025_0639 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ABP69232.1 | moaA | Rsph17025_0326 | Rsph17025_1577 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.805 |
ABP69232.1 | ndk | Rsph17025_0326 | Rsph17025_1127 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.920 |
ABP69232.1 | ribA | Rsph17025_0326 | Rsph17025_3129 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.811 |
ABP69232.1 | ribB | Rsph17025_0326 | Rsph17025_0420 | PFAM: metal-dependent phosphohydrolase, HD sub domain. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.847 |
ABP69900.1 | folE2 | Rsph17025_0999 | Rsph17025_0639 | Hypothetical protein. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.723 |
ABP70010.1 | ABP69232.1 | Rsph17025_1109 | Rsph17025_0326 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | PFAM: metal-dependent phosphohydrolase, HD sub domain. | 0.927 |
ABP70010.1 | ABP71374.1 | Rsph17025_1109 | Rsph17025_2486 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | 0.900 |
ABP70010.1 | ABP71464.1 | Rsph17025_1109 | Rsph17025_2576 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | (p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.927 |
ABP70010.1 | folE2 | Rsph17025_1109 | Rsph17025_0639 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.800 |
ABP70010.1 | moaA | Rsph17025_1109 | Rsph17025_1577 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | GTP cyclohydrolase subunit MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.807 |
ABP70010.1 | ndk | Rsph17025_1109 | Rsph17025_1127 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |
ABP70010.1 | ribA | Rsph17025_1109 | Rsph17025_3129 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.800 |
ABP70010.1 | ribB | Rsph17025_1109 | Rsph17025_0420 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.839 |
ABP70411.1 | folE2 | Rsph17025_1517 | Rsph17025_0639 | TIGRFAM: cobalamin biosynthesis protein CobW; PFAM: cobalamin synthesis protein, P47K; cobalamin synthesis CobW domain protein. | GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. | 0.723 |
ABP71374.1 | ABP69232.1 | Rsph17025_2486 | Rsph17025_0326 | PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | PFAM: metal-dependent phosphohydrolase, HD sub domain. | 0.905 |
ABP71374.1 | ABP70010.1 | Rsph17025_2486 | Rsph17025_1109 | PFAM: pyruvate kinase; Belongs to the pyruvate kinase family. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase. | 0.900 |