node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABP68920.1 | ABP69297.1 | Rsph17025_0008 | Rsph17025_0391 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: aminotransferase, class I and II. | 0.559 |
ABP68920.1 | ABP71967.1 | Rsph17025_0008 | Rsph17025_3083 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: aminotransferase, class I and II. | 0.566 |
ABP68920.1 | hisA | Rsph17025_0008 | Rsph17025_2251 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.902 |
ABP68920.1 | hisB | Rsph17025_0008 | Rsph17025_2249 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: imidazoleglycerol-phosphate dehydratase. | 0.918 |
ABP68920.1 | hisC | Rsph17025_0008 | Rsph17025_2213 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.566 |
ABP68920.1 | hisD | Rsph17025_0008 | Rsph17025_0593 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.790 |
ABP68920.1 | hisE | Rsph17025_0008 | Rsph17025_2253 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.737 |
ABP68920.1 | hisF | Rsph17025_0008 | Rsph17025_2252 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.920 |
ABP68920.1 | hisH | Rsph17025_0008 | Rsph17025_2250 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.896 |
ABP68920.1 | hisI | Rsph17025_0008 | Rsph17025_1163 | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.912 |
ABP69297.1 | ABP68920.1 | Rsph17025_0391 | Rsph17025_0008 | PFAM: aminotransferase, class I and II. | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.559 |
ABP69297.1 | hisA | Rsph17025_0391 | Rsph17025_2251 | PFAM: aminotransferase, class I and II. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.896 |
ABP69297.1 | hisB | Rsph17025_0391 | Rsph17025_2249 | PFAM: aminotransferase, class I and II. | PFAM: imidazoleglycerol-phosphate dehydratase. | 0.911 |
ABP69297.1 | hisD | Rsph17025_0391 | Rsph17025_0593 | PFAM: aminotransferase, class I and II. | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.910 |
ABP69297.1 | hisE | Rsph17025_0391 | Rsph17025_2253 | PFAM: aminotransferase, class I and II. | PFAM: phosphoribosyl-ATP pyrophosphohydrolase. | 0.907 |
ABP69297.1 | hisF | Rsph17025_0391 | Rsph17025_2252 | PFAM: aminotransferase, class I and II. | Imidazole glycerol phosphate synthase subunit hisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. | 0.908 |
ABP69297.1 | hisH | Rsph17025_0391 | Rsph17025_2250 | PFAM: aminotransferase, class I and II. | Imidazole glycerol phosphate synthase subunit hisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. | 0.914 |
ABP69297.1 | hisI | Rsph17025_0391 | Rsph17025_1163 | PFAM: aminotransferase, class I and II. | phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. | 0.912 |
ABP71967.1 | ABP68920.1 | Rsph17025_3083 | Rsph17025_0008 | PFAM: aminotransferase, class I and II. | TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: Haloacid dehalogenase domain protein hydrolase. | 0.566 |
ABP71967.1 | hisA | Rsph17025_3083 | Rsph17025_2251 | PFAM: aminotransferase, class I and II. | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein. | 0.924 |