node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ABQ93624.1 | ABQ94569.1 | PsycPRwf_0670 | PsycPRwf_1628 | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Belongs to the globin family. | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | 0.453 |
ABQ94569.1 | ABQ93624.1 | PsycPRwf_1628 | PsycPRwf_0670 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | PFAM: globin; oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; Belongs to the globin family. | 0.453 |
ABQ94569.1 | ABQ94571.1 | PsycPRwf_1628 | PsycPRwf_1630 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.918 |
ABQ94569.1 | ABQ94572.1 | PsycPRwf_1628 | PsycPRwf_1631 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.762 |
ABQ94569.1 | ABQ94575.1 | PsycPRwf_1628 | PsycPRwf_1634 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin. | 0.526 |
ABQ94569.1 | hscB | PsycPRwf_1628 | PsycPRwf_1632 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.861 |
ABQ94569.1 | iscS | PsycPRwf_1628 | PsycPRwf_1629 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.988 |
ABQ94569.1 | nfuA | PsycPRwf_1628 | PsycPRwf_1847 | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.600 |
ABQ94571.1 | ABQ94569.1 | PsycPRwf_1630 | PsycPRwf_1628 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | 0.918 |
ABQ94571.1 | ABQ94572.1 | PsycPRwf_1630 | PsycPRwf_1631 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.977 |
ABQ94571.1 | ABQ94575.1 | PsycPRwf_1630 | PsycPRwf_1634 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin. | 0.977 |
ABQ94571.1 | hscB | PsycPRwf_1630 | PsycPRwf_1632 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.992 |
ABQ94571.1 | iscS | PsycPRwf_1630 | PsycPRwf_1629 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.999 |
ABQ94571.1 | nfuA | PsycPRwf_1630 | PsycPRwf_1847 | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.974 |
ABQ94572.1 | ABQ94569.1 | PsycPRwf_1631 | PsycPRwf_1628 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | TIGRFAM: putative transcriptional regulator, Rrf2 family; PFAM: protein of unknown function UPF0074. | 0.762 |
ABQ94572.1 | ABQ94571.1 | PsycPRwf_1631 | PsycPRwf_1630 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | FeS cluster assembly scaffold IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.977 |
ABQ94572.1 | ABQ94575.1 | PsycPRwf_1631 | PsycPRwf_1634 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | TIGRFAM: ferredoxin, 2Fe-2S type, ISC system; PFAM: ferredoxin. | 0.885 |
ABQ94572.1 | hscB | PsycPRwf_1631 | PsycPRwf_1632 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.937 |
ABQ94572.1 | iscS | PsycPRwf_1631 | PsycPRwf_1629 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | Cysteine desulfurase IscS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins. | 0.886 |
ABQ94572.1 | nfuA | PsycPRwf_1631 | PsycPRwf_1847 | Iron-sulfur cluster assembly protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | HesB/YadR/YfhF-family protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.482 |