STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_0010PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding; KEGG: aeh:Mlg_1400 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding. (325 aa)    
Predicted Functional Partners:
Hhal_1267
Glycerate 2-kinase; PFAM: MOFRL domain protein; KEGG: eba:ebA4615 hydroxypyruvate reductase.
 
 0.939
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.913
Hhal_0221
PFAM: FAD linked oxidase domain protein; KEGG: aeh:Mlg_1894 FAD linked oxidase domain protein.
   
 0.911
Hhal_0222
PFAM: FAD linked oxidase domain protein; KEGG: aeh:Mlg_1895 FAD linked oxidase domain protein.
   
 0.911
Hhal_1402
TIGRFAM: isocitrate lyase; PFAM: isocitrate lyase and phosphorylmutase; KEGG: xac:XAC0257 isocitrate lyase.
     
 0.909
Hhal_0223
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; protein of unknown function DUF224, cysteine-rich region domain protein; KEGG: aeh:Mlg_1896 protein of unknown function DUF224, cysteine-rich region domain protein.
    
  0.905
gph
Phosphoglycolate phosphatase; Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress. Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family.
    
  0.902
Hhal_0066
PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase.
     
 0.698
Hhal_1029
Allosteric NADP-dependent malic enzyme; Phosphate acetyltransferase; PFAM: phosphate acetyl/butaryl transferase; malic enzyme domain protein; malic enzyme, NAD-binding; KEGG: aeh:Mlg_0246 malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)).
   
 
 0.675
Hhal_0009
PFAM: NAD-dependent epimerase/dehydratase; short-chain dehydrogenase/reductase SDR; Male sterility C-terminal domain; KR; KEGG: aeh:Mlg_1401 short-chain dehydrogenase/reductase SDR.
 
 
   0.643
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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