Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_0261TIGRFAM: HAD-superfamily hydrolase, subfamily IA, variant 1; PFAM: Haloacid dehalogenase domain protein hydrolase; KEGG: aeh:Mlg_1990 HAD-superfamily hydrolase, subfamily IA, variant 1. (245 aa)    
Predicted Functional Partners:
Hhal_0900
Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
    
 0.935
Hhal_1837
KEGG: aeh:Mlg_0851 riboflavin biosynthesis protein RibF; TIGRFAM: riboflavin biosynthesis protein RibF; PFAM: Riboflavin kinase / FAD synthetase; cytidylyltransferase; Belongs to the ribF family.
  
 
 0.918
ribH
6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family.
     
 0.902
Hhal_0899
TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: aeh:Mlg_0376 riboflavin synthase, alpha subunit.
   
 
  0.901
dnaQ
DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease.
       0.795
Hhal_0260
PFAM: protein of unknown function DUF523; Protein of unknown function DUF1722; KEGG: aeh:Mlg_1208 protein of unknown function DUF1722.
       0.659
Hhal_0256
Quinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
 
   
 0.506
Hhal_0257
PFAM: molybdopterin binding domain; KEGG: aeh:Mlg_1211 molybdopterin binding domain.
       0.500
Hhal_1201
PFAM: protein of unknown function DUF484; KEGG: aeh:Mlg_0062 protein of unknown function DUF484.
 
    0.488
Hhal_0263
KEGG: dar:Daro_1501 nitrogenase MoFe cofactor biosynthesis protein NifE; TIGRFAM: nitrogenase MoFe cofactor biosynthesis protein NifE; PFAM: oxidoreductase/nitrogenase, component 1; Belongs to the NifD/NifK/NifE/NifN family.
       0.471
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.