STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_0556KEGG: ret:RHE_CH00325 cysteine synthase protein; TIGRFAM: cysteine synthases; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit. (323 aa)    
Predicted Functional Partners:
Hhal_1794
TIGRFAM: serine O-acetyltransferase; KEGG: aeh:Mlg_1246 serine O-acetyltransferase.
 
 0.993
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
 
 0.979
Hhal_0187
Flavodoxin/nitric oxide synthase; PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; PepSY-associated TM helix domain protein; flavodoxin/nitric oxide synthase; KEGG: aeh:Mlg_1892 flavodoxin/nitric oxide synthase.
  
 
 0.965
cysC-2
Adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
  
  
 0.928
cysS
KEGG: aeh:Mlg_1810 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: cysteinyl-tRNA synthetase, class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family.
  
 
 0.920
serC
Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.914
Hhal_1694
PFAM: Pyridoxal-5'-phosphate-dependent enzyme, beta subunit; KEGG: aeh:Mlg_1718 pyridoxal-5'-phosphate-dependent enzyme, beta subunit.
  
  
 
0.913
Hhal_2154
Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.907
Hhal_0543
PFAM: aminotransferase, class I and II; KEGG: aeh:Mlg_1087 aminotransferase, class I and II.
    
 0.903
Hhal_1163
Sulfide dehydrogenase (flavocytochrome), flavoprotein subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: aeh:Mlg_1267 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
     
 0.903
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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