STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_0609Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein. (125 aa)    
Predicted Functional Partners:
Hhal_0471
PFAM: CheW domain protein; KEGG: aeh:Mlg_0991 CheW protein.
  
     0.770
Hhal_0475
Chemotaxis phosphatase, CheZ; Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P).
  
     0.707
Hhal_0521
PFAM: MCP methyltransferase, CheR-type; Methyltransferase type 11; KEGG: aeh:Mlg_0892 MCP methyltransferase, CheR-type.
  
 
   0.691
Hhal_0522
Putative CheW protein; PFAM: response regulator receiver; CheW domain protein; KEGG: aeh:Mlg_0891 response regulator receiver modulated CheW protein.
  
     0.678
folD
5,10-methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.655
Hhal_0370
PFAM: MCP methyltransferase, CheR-type; KEGG: aeh:Mlg_1118 MCP methyltransferase/methylesterase, CheR/CheB with PAS/PAC sensor.
    
   0.640
Hhal_2162
MCP methyltransferase, CheR-type; Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP.
    
   0.640
Hhal_0331
KEGG: pat:Patl_0168 MSHA biogenesis protein MshJ.
  
     0.638
Hhal_1716
PFAM: CheB methylesterase; MCP methyltransferase, CheR-type; KEGG: mag:amb3654 hypothetical 1041 kDa protein in HypE 3'region.
    
   0.634
Hhal_0488
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
  
    0.633
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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