STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Hhal_0638Phage DNA replication protein (predicted replicative helicase loader); PFAM: IstB domain protein ATP-binding protein; SMART: AAA ATPase; KEGG: plu:plu3472 hypothetical protein. (257 aa)    
Predicted Functional Partners:
Hhal_0612
PFAM: Integrase, catalytic region; KEGG: hch:HCH_06236 transposase, IS21 family.
 
 
 0.841
Hhal_0653
DnaB domain protein helicase, C-terminal domain protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
  
 
 0.838
Hhal_0639
Hypothetical protein; KEGG: lpn:lpg1005 LvrA.
  
    0.795
Hhal_0641
Hypothetical protein.
       0.774
Hhal_0640
KEGG: plu:plu1034 hypothetical protein.
       0.773
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.628
dnaA
Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
    
 
 0.573
Hhal_0642
KEGG: rme:Rmet_2292 hypothetical protein.
       0.560
Hhal_0637
PFAM: protein of unknown function DUF192.
       0.542
Hhal_0643
PFAM: Cobyrinic acid a,c-diamide synthase; KEGG: eba:ebA381 probable chromosome partitioning related protein.
       0.481
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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