STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_0803PFAM: Dual specificity protein phosphatase; KEGG: gme:Gmet_0085 protein tyrosine/serine phosphatase. (182 aa)    
Predicted Functional Partners:
kdkA
Lipopolysaccharide kinase; Catalyzes the ATP-dependent phosphorylation of the 3-deoxy-D- manno-octulosonic acid (Kdo) residue in Kdo-lipid IV(A) at the 4-OH position; Belongs to the protein kinase superfamily. KdkA/RfaP family.
   
 0.871
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.789
Hhal_1844
PFAM: Ankyrin; KEGG: rno:294988 ankyrin repeat domain 50 (predicted).
 
 
 0.589
Hhal_0198
PFAM: Ankyrin; KEGG: aeh:Mlg_2666 ankyrin.
 
 
 0.580
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 
 0.574
Hhal_0804
KEGG: aeh:Mlg_2804 Mn2+-dependent serine/threonine protein kinase.
  
    0.558
Hhal_0052
PFAM: AMP-dependent synthetase and ligase; phospholipid/glycerol acyltransferase; KEGG: aeh:Mlg_1601 AMP-dependent synthetase and ligase.
  
 0.509
Hhal_1197
Bis(5'-nucleosyl)-tetraphosphatase (symmetrical); Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family.
    
 
 0.479
cobB
PFAM: Silent information regulator protein Sir2; KEGG: rxy:Rxyl_1341 silent information regulator protein Sir2; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.441
Hhal_1897
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: aeh:Mlg_2001 TPR repeat-containing protein.
  
     0.415
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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