Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Hhal_1012Penicillin-binding protein 6, Serine peptidase, MEROPS family S11; PFAM: beta-lactamase; peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: aeh:Mlg_0176 serine-type D-Ala-D-Ala carboxypeptidase; Belongs to the peptidase S11 family. (392 aa)    
Predicted Functional Partners:
mrdA
Peptidoglycan glycosyltransferase; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
 
 
 0.996
ftsI
Peptidoglycan synthetase FtsI; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily.
  
 
 0.948
Hhal_2253
KEGG: aeh:Mlg_2754 penicillin-binding protein, 1A family; TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase, family 51; penicillin-binding protein, transpeptidase.
     
 0.927
lipB
Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
 
    0.858
Hhal_1014
PFAM: protein of unknown function DUF493; KEGG: aeh:Mlg_0178 protein of unknown function DUF493; Belongs to the UPF0250 family.
  
    0.846
Hhal_1013
Branched chain amino acid: 2-keto-4-methylthiobutyrate aminotransferase; PFAM: aminotransferase, class IV; KEGG: aeh:Mlg_0177 aminotransferase, class IV.
       0.833
mrdB
Cell elongation-specific peptidoglycan biosynthesis regulator RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily.
 
   
 0.793
Hhal_1010
TIGRFAM: lytic murein transglycosylase B; KEGG: aeh:Mlg_0174 lytic murein transglycosylase B.
 
   
 0.764
rlpA
Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides.
  
  
 0.752
Hhal_1006
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
 
  
 0.684
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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