Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_1016KEGG: aeh:Mlg_0195 succinylglutamate desuccinylase/aspartoacylase. (339 aa)    
Predicted Functional Partners:
Hhal_1017
PFAM: glutamate--cysteine ligase, GCS2; KEGG: aeh:Mlg_0196 hypothetical protein.
 
     0.943
Hhal_1018
PFAM: Nucleotidyl transferase; KEGG: aeh:Mlg_0197 nucleotidyl transferase.
       0.669
Hhal_1019
PFAM: aminoglycoside phosphotransferase; KEGG: aeh:Mlg_0198 aminoglycoside phosphotransferase.
       0.666
Hhal_1547
KEGG: aeh:Mlg_0107 VanZ family protein.
  
     0.532
lptD
Organic solvent tolerance protein; Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane.
       0.473
surA
PpiC-type peptidyl-prolyl cis-trans isomerase; Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation.
       0.473
pdxA
4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP).
       0.473
Hhal_0533
PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein; KEGG: aeh:Mlg_1155 tetratricopeptide TPR_2 repeat protein.
  
     0.454
Hhal_1523
KEGG: aeh:Mlg_0149 hypothetical protein.
  
     0.447
Hhal_2286
KEGG: aeh:Mlg_2527 hypothetical protein.
  
     0.405
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
Server load: low (14%) [HD]