| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hhal_0026 | Hhal_2290 | Hhal_0026 | Hhal_2290 | KEGG: aeh:Mlg_1358 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | KEGG: aeh:Mlg_0262 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: CBS domain containing protein; isocitrate/isopropylmalate dehydrogenase. | 0.897 |
| Hhal_0026 | argH | Hhal_0026 | Hhal_1024 | KEGG: aeh:Mlg_1358 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: aeh:Mlg_2673 argininosuccinate lyase. | 0.919 |
| Hhal_0026 | mdh | Hhal_0026 | Hhal_0830 | KEGG: aeh:Mlg_1358 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.848 |
| Hhal_2290 | Hhal_0026 | Hhal_2290 | Hhal_0026 | KEGG: aeh:Mlg_0262 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: CBS domain containing protein; isocitrate/isopropylmalate dehydrogenase. | KEGG: aeh:Mlg_1358 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase C-terminal domain protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.897 |
| Hhal_2290 | argD | Hhal_2290 | Hhal_0727 | KEGG: aeh:Mlg_0262 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: CBS domain containing protein; isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: aeh:Mlg_1102 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.443 |
| Hhal_2290 | argH | Hhal_2290 | Hhal_1024 | KEGG: aeh:Mlg_0262 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: CBS domain containing protein; isocitrate/isopropylmalate dehydrogenase. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: aeh:Mlg_2673 argininosuccinate lyase. | 0.876 |
| Hhal_2290 | mdh | Hhal_2290 | Hhal_0830 | KEGG: aeh:Mlg_0262 isocitrate dehydrogenase, NADP-dependent; TIGRFAM: isocitrate dehydrogenase, NADP-dependent; PFAM: CBS domain containing protein; isocitrate/isopropylmalate dehydrogenase. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.970 |
| argA | argB | Hhal_2046 | Hhal_2296 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.992 |
| argA | argC | Hhal_2046 | Hhal_0880 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.995 |
| argA | argD | Hhal_2046 | Hhal_0727 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: aeh:Mlg_1102 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.964 |
| argA | argF | Hhal_2046 | Hhal_0726 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.966 |
| argA | argG | Hhal_2046 | Hhal_0725 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | PFAM: argininosuccinate synthase; KEGG: aeh:Mlg_0601 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.993 |
| argA | argH | Hhal_2046 | Hhal_1024 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: aeh:Mlg_2673 argininosuccinate lyase. | 0.986 |
| argA | argJ | Hhal_2046 | Hhal_2026 | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | Glutamate N-acetyltransferase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. | 0.999 |
| argB | argA | Hhal_2296 | Hhal_2046 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: amino-acid N-acetyltransferase; PFAM: GCN5-related N-acetyltransferase; aspartate/glutamate/uridylate kinase; KEGG: aeh:Mlg_0363 amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily. | 0.992 |
| argB | argC | Hhal_2296 | Hhal_0880 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.999 |
| argB | argD | Hhal_2296 | Hhal_0727 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: aeh:Mlg_1102 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. | 0.985 |
| argB | argF | Hhal_2296 | Hhal_0726 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Ornithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family. | 0.916 |
| argB | argG | Hhal_2296 | Hhal_0725 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | PFAM: argininosuccinate synthase; KEGG: aeh:Mlg_0601 argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. | 0.962 |
| argB | argH | Hhal_2296 | Hhal_1024 | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase; KEGG: aeh:Mlg_2673 argininosuccinate lyase. | 0.968 |