| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Hhal_0066 | Hhal_0180 | Hhal_0066 | Hhal_0180 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | 0.972 |
| Hhal_0066 | Hhal_0279 | Hhal_0066 | Hhal_0279 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.969 |
| Hhal_0066 | Hhal_1071 | Hhal_0066 | Hhal_1071 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | KEGG: aeh:Mlg_2604 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.958 |
| Hhal_0066 | Hhal_1493 | Hhal_0066 | Hhal_1493 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: csa:Csal_2644 acyl-CoA dehydrogenase-like protein. | 0.718 |
| Hhal_0066 | Hhal_1685 | Hhal_0066 | Hhal_1685 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | KEGG: bxe:Bxe_B0739 thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.959 |
| Hhal_0066 | Hhal_2251 | Hhal_0066 | Hhal_2251 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | KEGG: aeh:Mlg_2752 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.958 |
| Hhal_0066 | acsA | Hhal_0066 | Hhal_1895 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.972 |
| Hhal_0066 | leuA | Hhal_0066 | Hhal_0690 | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.969 |
| Hhal_0180 | Hhal_0066 | Hhal_0180 | Hhal_0066 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | 0.972 |
| Hhal_0180 | Hhal_0279 | Hhal_0180 | Hhal_0279 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | 0.910 |
| Hhal_0180 | Hhal_1071 | Hhal_0180 | Hhal_1071 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | KEGG: aeh:Mlg_2604 2-methylcitrate synthase/citrate synthase II; TIGRFAM: 2-methylcitrate synthase/citrate synthase II; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.931 |
| Hhal_0180 | Hhal_1685 | Hhal_0180 | Hhal_1685 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | KEGG: bxe:Bxe_B0739 thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.935 |
| Hhal_0180 | Hhal_2251 | Hhal_0180 | Hhal_2251 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | KEGG: aeh:Mlg_2752 citrate synthase I; TIGRFAM: citrate synthase I; PFAM: Citrate synthase; Belongs to the citrate synthase family. | 0.931 |
| Hhal_0180 | acsA | Hhal_0180 | Hhal_1895 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.918 |
| Hhal_0180 | leuA | Hhal_0180 | Hhal_0690 | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.910 |
| Hhal_0279 | Hhal_0066 | Hhal_0279 | Hhal_0066 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: 4Fe-4S ferredoxin, iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: rpa:RPA4721 possible+E2677 pyruvate-flavodoxin oxidoreductase. | 0.969 |
| Hhal_0279 | Hhal_0180 | Hhal_0279 | Hhal_0180 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: AMP-dependent synthetase and ligase; KEGG: aeh:Mlg_2650 AMP-dependent synthetase and ligase. | 0.910 |
| Hhal_0279 | Hhal_1493 | Hhal_0279 | Hhal_1493 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | PFAM: acyl-CoA dehydrogenase domain protein; Acyl-CoA dehydrogenase, type 2, C-terminal domain; KEGG: csa:Csal_2644 acyl-CoA dehydrogenase-like protein. | 0.475 |
| Hhal_0279 | Hhal_1685 | Hhal_0279 | Hhal_1685 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | KEGG: bxe:Bxe_B0739 thiolase; TIGRFAM: acetyl-CoA acetyltransferases; PFAM: Thiolase; Belongs to the thiolase-like superfamily. Thiolase family. | 0.937 |
| Hhal_0279 | acsA | Hhal_0279 | Hhal_1895 | TIGRFAM: homocitrate synthase; PFAM: pyruvate carboxyltransferase; KEGG: mag:amb1562 isopropylmalate/homocitrate/citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.910 |