close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_1900PFAM: cyclic nucleotide-binding; CBS domain containing protein; protein of unknown function DUF294, nucleotidyltransferase putative; KEGG: aeh:Mlg_2004 cyclic nucleotide-binding protein. (640 aa)    
Predicted Functional Partners:
Hhal_1902
KEGG: aeh:Mlg_2006 putative PAS/PAC sensor protein; TIGRFAM: PAS sensor protein; DNA polymerase III, epsilon subunit; PFAM: Exonuclease, RNase T and DNA polymerase III; PAS fold-4 domain protein; SMART: PAS domain containing protein; Exonuclease.
    0.861
Hhal_1904
Integral membrane sensor signal transduction histidine kinase; PFAM: Na+/solute symporter; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; KEGG: aeh:Mlg_0666 periplasmic sensor signal transduction histidine kinase.
 
    0.673
Hhal_1901
PFAM: response regulator receiver; KEGG: aeh:Mlg_0669 response regulator receiver protein.
 
     0.611
Hhal_0219
Protein of unknown function DUF299; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation.
  
  
 0.597
Hhal_1903
KEGG: aeh:Mlg_0667 hypothetical protein.
       0.582
Hhal_1905
PFAM: alpha/beta hydrolase fold; KEGG: aeh:Mlg_2510 alpha/beta hydrolase fold.
       0.548
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.512
Hhal_1899
PFAM: Na+/solute symporter; KEGG: aeh:Mlg_2003 Na+/solute symporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
     0.509
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.