node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Hhal_2006 | Hhal_2009 | Hhal_2006 | Hhal_2009 | KEGG: aeh:Mlg_0605 hypothetical protein. | PFAM: peptidase S16, lon domain protein; KEGG: aeh:Mlg_0602 peptidase S16, lon domain protein. | 0.790 |
Hhal_2006 | mpl | Hhal_2006 | Hhal_2007 | KEGG: aeh:Mlg_0605 hypothetical protein. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.800 |
Hhal_2006 | ubiX | Hhal_2006 | Hhal_2008 | KEGG: aeh:Mlg_0605 hypothetical protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.800 |
Hhal_2009 | Hhal_2006 | Hhal_2009 | Hhal_2006 | PFAM: peptidase S16, lon domain protein; KEGG: aeh:Mlg_0602 peptidase S16, lon domain protein. | KEGG: aeh:Mlg_0605 hypothetical protein. | 0.790 |
Hhal_2009 | mpl | Hhal_2009 | Hhal_2007 | PFAM: peptidase S16, lon domain protein; KEGG: aeh:Mlg_0602 peptidase S16, lon domain protein. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.820 |
Hhal_2009 | ubiX | Hhal_2009 | Hhal_2008 | PFAM: peptidase S16, lon domain protein; KEGG: aeh:Mlg_0602 peptidase S16, lon domain protein. | 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. | 0.821 |
ddl | mpl | Hhal_2088 | Hhal_2007 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | 0.959 |
ddl | mraY | Hhal_2088 | Hhal_2094 | D-alanine--D-alanine ligase; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.969 |
ddl | murB | Hhal_2088 | Hhal_0761 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.859 |
ddl | murB-2 | Hhal_2088 | Hhal_2089 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.986 |
ddl | murD | Hhal_2088 | Hhal_2093 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.974 |
ddl | murF | Hhal_2088 | Hhal_2095 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
ddl | murG | Hhal_2088 | Hhal_2091 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.983 |
mpl | Hhal_2006 | Hhal_2007 | Hhal_2006 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | KEGG: aeh:Mlg_0605 hypothetical protein. | 0.800 |
mpl | Hhal_2009 | Hhal_2007 | Hhal_2009 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | PFAM: peptidase S16, lon domain protein; KEGG: aeh:Mlg_0602 peptidase S16, lon domain protein. | 0.820 |
mpl | ddl | Hhal_2007 | Hhal_2088 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | D-alanine--D-alanine ligase; Cell wall formation. | 0.959 |
mpl | mraY | Hhal_2007 | Hhal_2094 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.779 |
mpl | murB | Hhal_2007 | Hhal_0761 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.780 |
mpl | murB-2 | Hhal_2007 | Hhal_2089 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | UDP-N-acetylmuramate dehydrogenase; Cell wall formation. | 0.875 |
mpl | murD | Hhal_2007 | Hhal_2093 | UDP-N-acetylmuramate; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.909 |