Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Hhal_2115PFAM: BolA family protein; KEGG: cyb:CYB_2713 BolA/YrbA family protein; Belongs to the BolA/IbaG family. (83 aa)    
Predicted Functional Partners:
Hhal_0729
TIGRFAM: glutaredoxin-like protein; PFAM: glutaredoxin; KEGG: aeh:Mlg_0595 glutaredoxin-like protein; Belongs to the glutaredoxin family. Monothiol subfamily.
 
 
 
 0.846
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
    0.844
hisG
ATP phosphoribosyltransferase (homohexameric); Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
  
    0.803
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.749
hisC-2
TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase, class I and II; KEGG: aeh:Mlg_2214 histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.724
Hhal_2116
KEGG: aeh:Mlg_2219 anti-sigma-factor antagonist.
       0.699
Hhal_2117
PFAM: toluene tolerance family protein; KEGG: aeh:Mlg_2220 toluene tolerance family protein.
       0.690
Hhal_2118
PFAM: Mammalian cell entry related domain protein; KEGG: aeh:Mlg_2221 mammalian cell entry related domain protein.
     
 0.684
Hhal_2120
PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: aeh:Mlg_2223 ABC transporter related.
     
 0.646
Hhal_2119
PFAM: protein of unknown function DUF140; KEGG: aeh:Mlg_2222 protein of unknown function DUF140.
       0.635
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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