Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_2167CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; KEGG: tcx:Tcr_1612 CheA signal transduction histidine kinase. (703 aa)    
Predicted Functional Partners:
Hhal_2166
PFAM: CheW domain protein; KEGG: sde:Sde_3106 biotin synthase.
 0.999
Hhal_0522
Putative CheW protein; PFAM: response regulator receiver; CheW domain protein; KEGG: aeh:Mlg_0891 response regulator receiver modulated CheW protein.
 
 0.997
cheB-2
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.997
Hhal_0470
PFAM: CheW domain protein; KEGG: aeh:Mlg_0992 CheW protein.
 0.996
Hhal_1716
PFAM: CheB methylesterase; MCP methyltransferase, CheR-type; KEGG: mag:amb3654 hypothetical 1041 kDa protein in HypE 3'region.
 
 0.996
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 
 0.995
Hhal_0476
PFAM: response regulator receiver; KEGG: aeh:Mlg_0986 response regulator receiver protein.
  
 0.993
Hhal_2165
PFAM: chemotaxis sensory transducer; KEGG: rpb:RPB_3522 methyl-accepting chemotaxis sensory transducer.
 
  0.989
Hhal_2168
PFAM: response regulator receiver; KEGG: hch:HCH_00454 FOG: CheY-like receiver.
 0.989
Hhal_2163
PFAM: chemotaxis sensory transducer; SMART: histidine kinase, HAMP region domain protein; KEGG: vch:VCA1092 methyl-accepting chemotaxis protein.
 
 0.987
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.