STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_2207PFAM: HDOD; KEGG: aeh:Mlg_2488 putative signal transduction protein. (281 aa)    
Predicted Functional Partners:
flgI
Flagellar P-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.590
Hhal_0488
Flagellar basal body-associated protein FliL; Controls the rotational direction of flagella during chemotaxis; Belongs to the FliL family.
 
     0.549
Hhal_0228
Putative signal transduction protein; PFAM: HDOD; KEGG: aeh:Mlg_1506 hypothetical protein.
  
     0.545
Hhal_0487
Flagellar motor switch protein FliM; FliM is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
 
    0.545
Hhal_0479
PFAM: GTP-binding signal recognition particle SRP54, G- domain; SMART: AAA ATPase; KEGG: aeh:Mlg_0983 GTP-binding signal recognition particle SRP54, G-domain.
 
     0.531
Hhal_1868
TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; histidine kinase, HAMP region domain protein; KEGG: mag:amb1945 response regulator.
 
      0.530
flgH
Flagellar L-ring protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
 
     0.529
Hhal_2206
TIGRFAM: polyhydroxyalkanoate synthesis repressor PhaR; PFAM: PHB accumulation regulatory domain protein; PHA accumulation regulator DNA-binding protein; KEGG: aeh:Mlg_2487 polyhydroxyalkonate synthesis repressor, PhaR.
       0.529
Hhal_0522
Putative CheW protein; PFAM: response regulator receiver; CheW domain protein; KEGG: aeh:Mlg_0891 response regulator receiver modulated CheW protein.
 
 
   0.525
Hhal_0609
Type IV pilus assembly PilZ; Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second-messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a possible effector protein.
  
    0.493
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.