STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Hhal_2312Diguanylate phosphodiesterase; PFAM: EAL domain protein; HDOD; KEGG: ace:Acel_0828 diguanylate phosphodiesterase. (423 aa)    
Predicted Functional Partners:
mutM
DNA-(apurinic or apyrimidinic site) lyase / Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
       0.747
Hhal_0173
Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s); KEGG: bja:bll7580 hypothetical protein; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; GAF domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
   
 0.532
Hhal_0512
KEGG: aeh:Mlg_0901 flagellar rod assembly protein/muramidase FlgJ; TIGRFAM: flagellar rod assembly protein/muramidase FlgJ; PFAM: Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase; SMART: Lysozyme subfamily 2.
 
     0.488
rpmG
PFAM: ribosomal protein L33; KEGG: aeh:Mlg_2642 ribosomal protein L33; Belongs to the bacterial ribosomal protein bL33 family.
       0.469
rpmB
PFAM: ribosomal protein L28; KEGG: aeh:Mlg_2641 ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
       0.469
Hhal_0511
TIGRFAM: flagellar hook-associated protein FlgK; PFAM: flagellar basal body rod protein; protein of unknown function DUF1078 domain protein; KEGG: aeh:Mlg_0902 flagellar hook-associated protein FlgK; Belongs to the flagella basal body rod proteins family.
 
     0.421
Hhal_0493
PFAM: flagellar hook-length control protein; KEGG: aeh:Mlg_0714 flagellar hook-length control protein.
  
     0.413
Your Current Organism:
Halorhodospira halophila
NCBI taxonomy Id: 349124
Other names: H. halophila SL1, Halorhodospira halophila DSM 244, Halorhodospira halophila SL 1, Halorhodospira halophila SL1, Halorhodospira halophila str. SL1, Halorhodospira halophila strain SL1
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