Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Dred_0331TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: oih:OB2344 PTS system, histidine-containing phosphocarrier protein (HPr protein). (87 aa)    
Predicted Functional Partners:
Dred_0330
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
Dred_0332
Glucose PTS system EIICBA or EIICB component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease, EIIA 1 domain; phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: cno:NT01CX_0332 PTS enzyme II, ABC component; TC 4.A.1.1.6; TC 4.A.1.1.6; TC 4.A.1.1.6.
 
 0.997
Dred_3055
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: bsu:BG12403 catabolite repression HPr-like protein.
  
  
  0.963
rpsG
SSU ribosomal protein S7P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family.
  
    0.640
Dred_0333
Transcriptional antiterminator, BglG family; PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: bld:BLi01597 transcriptional antiterminator essential for the expression of the ptsGHI operon; RBL02128.
 
 
 
 0.631
rpsL
SSU ribosomal protein S12P; With S4 and S5 plays an important role in translational accuracy.
  
    0.617
Dred_0381
PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; KEGG: chy:CHY_1144 pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.562
Dred_2312
PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; KEGG: chy:CHY_1144 pyruvate kinase; Belongs to the pyruvate kinase family.
  
  
 0.562
rpsR
SSU ribosomal protein S18P; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
  
    0.442
dinG
DNA polymerase III, epsilon subunit; 3'-5' exonuclease.
     
 0.405
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.