STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_0332Glucose PTS system EIICBA or EIICB component; TIGRFAM: PTS system, glucose subfamily, IIA subunit; PTS system, glucose-like IIB subunint; PFAM: sugar-specific permease, EIIA 1 domain; phosphotransferase system PTS, EIIB protein; phosphotransferase system, EIIC; KEGG: cno:NT01CX_0332 PTS enzyme II, ABC component; TC 4.A.1.1.6; TC 4.A.1.1.6; TC 4.A.1.1.6. (622 aa)    
Predicted Functional Partners:
Dred_0330
Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
 
 0.999
Dred_0331
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: oih:OB2344 PTS system, histidine-containing phosphocarrier protein (HPr protein).
 
 0.998
Dred_3055
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphocarrier HPr protein; KEGG: bsu:BG12403 catabolite repression HPr-like protein.
  
 0.994
Dred_0333
Transcriptional antiterminator, BglG family; PFAM: CAT RNA-binding domain protein; PRD domain protein; KEGG: bld:BLi01597 transcriptional antiterminator essential for the expression of the ptsGHI operon; RBL02128.
 
 0.992
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: chy:CHY_0239 glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.970
Dred_1398
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: swo:Swol_2154 phosphomannomutase.
     
 0.944
Dred_3126
Phosphomannomutase; PFAM: phosphoglucomutase/phosphomannomutase C terminal; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain II; phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain III; KEGG: pca:Pcar_1779 phosphomannomutase.
     
 0.944
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate.
  
 
 0.941
Dred_3176
KEGG: chy:CHY_0128 fructose-1,6-bisphosphate aldolase, class II; TIGRFAM: ketose-bisphosphate aldolases; fructose-1,6-bisphosphate aldolase, class II; PFAM: ketose-bisphosphate aldolase, class-II.
 
 
 0.926
Dred_1458
PFAM: alpha amylase, catalytic region; SMART: alpha amylase, catalytic sub domain; KEGG: dsy:DSY2035 hypothetical protein; Belongs to the glycosyl hydrolase 13 family.
  
  
 0.925
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.