STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_0384PFAM: histidine kinase, HAMP region domain protein; Cache domain protein; chemotaxis sensory transducer; KEGG: cac:CAC2821 methyl-accepting chemotaxis protein. (644 aa)    
Predicted Functional Partners:
cheB
Response regulator receiver modulated CheB methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
 0.983
Dred_2440
CheA signal transduction histidine kinase; PFAM: CheW domain protein; ATP-binding region, ATPase domain protein domain protein; Signal transducing histidine kinase, homodimeric; Hpt domain protein; P2 response regulator binding domain protein; KEGG: chy:CHY_0967 chemotaxis protein CheA.
 
 0.982
cheD
CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  0.977
Dred_2154
PFAM: CheW domain protein; KEGG: chy:CHY_0966 chemotaxis protein CheW.
 
 0.976
Dred_2441
PFAM: CheW domain protein; KEGG: mta:Moth_0741 CheW protein.
 
 0.976
Dred_2384
Protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase, CheR-type; KEGG: mta:Moth_0801 MCP methyltransferase, CheR-type.
 0.942
Dred_2382
PFAM: response regulator receiver; KEGG: chy:CHY_1018 chemotaxis response regulator.
  
 
  0.931
Dred_1268
PFAM: MCP methyltransferase, CheR-type; KEGG: ana:all1848 similar to methyltransferase.
 
 0.884
Dred_1267
Integral membrane sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: bce:BC1008 two component system histidine kinase.
  
 0.867
Dred_2383
CheC, inhibitor of MCP methylation; PFAM: CheC domain protein; KEGG: chy:CHY_1017 chemotaxis protein CheC.
 
 
 0.635
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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