STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
bioBBiotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. (321 aa)    
Predicted Functional Partners:
birA
biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.963
Dred_2151
Iron-only hydrogenase maturation protein HydE; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB; KEGG: mta:Moth_1735 radical SAM.
  
  
 
0.909
Dred_2058
PFAM: aminotransferase class-III; KEGG: tte:TTE2339 PLP-dependent aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
 
 
  
 0.727
argD
TIGRFAM: acetylornithine and succinylornithine aminotransferases; PFAM: aminotransferase class-III; KEGG: mta:Moth_2287 acetylornithine and succinylornithine aminotransferases; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily.
 
 
  
 0.661
Dred_0429
PFAM: protein of unknown function DUF1624; KEGG: mba:Mbar_A1147 hypothetical protein.
  
    0.580
Dred_0169
PFAM: BioY protein; KEGG: swo:Swol_0108 hypothetical protein.
  
  
 0.573
thiC
Hydroxymethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
  
 0.541
Dred_2152
Iron-only hydrogenase maturation protein HydF; TIGRFAM: small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related; Miro domain protein; KEGG: mta:Moth_1277 small GTP-binding protein domain.
     
 0.492
Dred_2162
uroporphyrinogen-III C-methyltransferase / uroporphyrinogen-III synthase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Uroporphyrinogen III synthase HEM4; KEGG: dsy:DSY2224 hypothetical protein.
 
   
 0.492
Dred_1654
NAD(P)-dependent iron-only hydrogenase catalytic subunit; TIGRFAM: hydrogenases, Fe-only; PFAM: ferredoxin; 4Fe-4S ferredoxin, iron-sulfur binding domain protein; iron hydrogenase, small subunit; hydrogenase large subunit domain protein; KEGG: tte:TTE0894 NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G).
  
  
 0.490
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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