STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sepF1Protein of unknown function DUF552; Cell division protein that is part of the divisome complex and is recruited early to the Z-ring. Probably stimulates Z-ring formation, perhaps through the cross-linking of FtsZ protofilaments. Its function overlaps with FtsA. (147 aa)    
Predicted Functional Partners:
Dred_0712
Alanine racemase domain protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis; Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.
  
  
 0.961
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
  
 
 0.945
Dred_0714
PFAM: protein of unknown function YGGT; KEGG: chy:CHY_2040 hypothetical protein.
  
  
 0.924
Dred_0716
PFAM: DivIVA family protein; KEGG: tte:TTE1596 Cell division initiation protein.
  
  
 0.890
Dred_0715
PFAM: RNA-binding S4 domain protein; KEGG: chy:CHY_2039 S4 domain protein.
 
  
 0.859
Dred_0711
KEGG: mta:Moth_0857 hypothetical protein.
       0.801
Dred_0773
PFAM: protein of unknown function DUF965; KEGG: mta:Moth_1643 protein of unknown function DUF965; Belongs to the UPF0297 family.
  
  
 0.713
Dred_0683
PFAM: cell division protein FtsA; KEGG: ppd:Ppro_3284 cell division protein FtsA.
  
 
 0.686
Dred_1368
KEGG: cac:CAC1013 FtsA related protein, predicted ATPase of the HSP70 family.
  
 
 0.673
Dred_1879
Aluminum resistance family protein; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; Aluminium resistance family protein; KEGG: gka:GK1325 aluminum resistance protein.
 
     0.647
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.