STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_1102Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11, D-alanyl-D-alanine carboxypeptidase 1; Penicillin-binding protein 5 domain protein; KEGG: dsy:DSY2305 hypothetical protein. (403 aa)    
Predicted Functional Partners:
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
   
 0.644
deoB
Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family.
 
     0.604
Dred_1105
RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
     0.596
Dred_1103
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; Anti-sigma factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: gka:GK2310 anti-sigma F factor antagonist (stage II sporulation protein AA); Belongs to the anti-sigma-factor antagonist family.
     
 0.588
Dred_1101
Thymidine phosphorylase; KEGG: cno:NT01CX_1499 pyrimidine-nucleoside phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase, family 3; Pyrimidine nucleoside phosphorylase, C-terminal domain.
       0.570
Dred_0669
Stage V sporulation protein D; KEGG: chy:CHY_2075 penicillin-binding protein 2B; TIGRFAM: stage V sporulation protein D; PFAM: penicillin-binding protein, transpeptidase; Penicillin-binding protein, dimerisation domain; PASTA domain containing protein.
  
 0.540
Dred_1107
PFAM: Stage V sporulation AD family protein; KEGG: mta:Moth_1375 stage V sporulation AD.
 
   
 0.506
Dred_1106
PFAM: SpoVA protein; KEGG: ctc:CTC02245 stage V sporulation protein AC.
 
  
 0.484
Dred_1140
PFAM: nucleoside recognition domain protein; KEGG: mta:Moth_1356 nucleoside recognition.
  
  
 0.484
Dred_1141
PFAM: nucleoside recognition domain protein; KEGG: mta:Moth_1355 nucleoside recognition.
  
  
 0.476
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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