STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_1105RNA polymerase, sigma subunit, RpoX/SigF; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (260 aa)    
Predicted Functional Partners:
spoIIAB
Putative anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
 
 
 0.988
Dred_1103
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; Anti-sigma factor antagonist; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: gka:GK2310 anti-sigma F factor antagonist (stage II sporulation protein AA); Belongs to the anti-sigma-factor antagonist family.
 
  
 0.982
Dred_2438
KEGG: maq:Maqu_1174 anti-sigma-28 factor, FlgM.
  
 
 0.915
Dred_1106
PFAM: SpoVA protein; KEGG: ctc:CTC02245 stage V sporulation protein AC.
 
   
 0.877
Dred_1107
PFAM: Stage V sporulation AD family protein; KEGG: mta:Moth_1375 stage V sporulation AD.
 
    0.852
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.845
Dred_1108
PFAM: SpoVA protein; KEGG: swo:Swol_0628 SpoVA protein.
 
     0.839
Dred_2411
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
 
 0.809
Dred_2410
TIGRFAM: flagellar basal-body rod protein FlgC; PFAM: protein of unknown function DUF1078 domain protein; KEGG: mta:Moth_0769 flagellar basal-body rod protein FlgC; Belongs to the flagella basal body rod proteins family.
  
 
 0.805
Dred_1110
PFAM: Bacillus/Clostridium GerA spore germination protein; KEGG: dsy:DSY2298 hypothetical protein.
 
    0.797
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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