STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dred_1518Potassium/proton antiporter membrane subunit, CPA2 family; PFAM: sodium/hydrogen exchanger; KEGG: mta:Moth_2065 sodium/hydrogen exchanger; TC 2.A.37.5.2. (411 aa)    
Predicted Functional Partners:
Dred_1517
Potassium/proton antiporter regulatory subunit, CPA2 family; PFAM: TrkA-C domain protein; KEGG: mta:Moth_2066 TrkA-C; TC 2.A.37.5.2.
 
  
 0.985
Dred_0471
PFAM: TrkA-N domain protein; TrkA-C domain protein; Ion transport 2 domain protein,; KEGG: btk:BT9727_5075 potassium channel protein.
    
 0.791
Dred_2944
PFAM: Cl- channel, voltage-gated family protein; TrkA-C domain protein; KEGG: cno:NT01CX_0195 voltage gated chloride channel family protein.
     
 0.612
Dred_1692
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein domain protein; Haloacid dehalogenase domain protein hydrolase; cation transporting ATPase domain protein; E1-E2 ATPase-associated domain protein; KEGG: dsy:DSY2749 hypothetical protein.
 
 
 0.524
guaB
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
     
 0.499
Dred_2145
KEGG: ava:Ava_4779 multi-sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase A domain protein domain protein; Hpt domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
     
 0.437
Dred_1556
GAF sensor hybrid histidine kinase; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region, ATPase domain protein domain protein; histidine kinase, HAMP region domain protein; histidine kinase A domain protein domain protein; KEGG: sth:STH843 two-component sensor histidine kinase.
     
 0.427
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.
     
 0.420
Dred_2967
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; SirA family protein; Rhodanese domain protein; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: bfr:BF0575 pyridine nucleotide-disulphide oxidoreductase; Belongs to the sulfur carrier protein TusA family.
  
  
 0.414
Dred_1497
KEGG: cph:Cpha266_1183 conserved hypothetical protein.
 
     0.404
Your Current Organism:
Desulfotomaculum reducens
NCBI taxonomy Id: 349161
Other names: D. reducens MI-1, Desulfotomaculum reducens MI-1, Desulfotomaculum reducens str. MI-1, Desulfotomaculum reducens strain MI-1
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